B.6B_CellSpecialization_Approaching – 03
To understand the process, let us look at the journey that a red blood cell (RBC) takes from start to finish. The life of a RBC, like cells in most multicellular organisms, begins with a fertilized egg cell. The fertilized egg divides to form two identical cells. After a few rounds of cell division, a small cluster of identical cells forms. The cluster is simple and not well organized.


After a few more cell divisions, the cells in the cluster differentiate and become more organized. Some become stem cells. Stem cells are cells that can form into many different types of cells. The location of stem cells in the germ layers is important. The red blood cells will come from cells in the bone marrow or spleen of most animals.
At the right time, stem cells will differentiate into more specific stem cells. One type will go on to form muscle tissue. A different type will form bone. A very specific type of stem cell will form blood cells. These stem cells will form in the bone marrow or spleen. They will continue to divide to form many cells. They will differentiate at certain times to become the different types of blood cells. This is the finish line for the formation of the mature RBC.


Environmental factors can affect cell differentiation. The color pattern of a Siamese cat’s hair depends on enzymes that are sensitive to temperature. The enzymes are involved in pigment production. Exposure to toxic chemicals in the early stages can block chemical signals. This blockage can cause abnormal structures in developing offspring.

